منابع مشابه
A Notch Sweeter
Notch is a key signaling protein mediating cell-fate decisions during development. In this issue, Acar et al. (2008) describe a new gene called rumi that is required for Notch signaling in Drosophila. This gene encodes an O-glucosyltransferase that attaches glucose sugars to serine residues in the multiple EGF domains of the extracellular region of Notch. This modification by Rumi likely influe...
متن کاملSweeter tumors with EGFR
Robo keeps axons moving F or migrating axons, attraction becomes repulsion with the fl ip of an alternatively spliced switch, according to Zhe Chen, Marc Tessier-Lavigne (Genentech Inc., San Francisco, CA), and colleagues. A melange of chemoattractants and repellants guides growing axons to their targets. Axons that cross the midline of the spinal cord on their way toward the nascent brain, how...
متن کاملNICU procedures are getting sweeter: development of a sucrose protocol for neonatal procedural pain.
Neonates in the neonatal intensive care nursery experience multiple, painful, tissue-damaging procedures daily. Pain among neonates is often underestimated and untreated, producing untoward consequences. A literature review established strong evidence supporting the use of sucrose as an analgesic for minor procedural pain among neonates. A review of unit practices and nurses' experiential evide...
متن کاملAre Those with Darker Personality Traits more Willing to Corrupt When They Feel Anxious?
This unprecedented research endeavors to investigate the relationship between dark personality traits (i.e., narcissism, Machiavellianism, and psychopathy) and corruption intention through the mediation of anxiety. Based on the resource conservation theory, it is hypothesized that those higher in dark personality traits are more inclined to corrupt when they feel anxious. Having collected data...
متن کاملPK-M2 Makes Cells Sweeter on HIF1
The transcription factor hypoxia-inducible factor 1 (HIF1) facilitates the induction of enzymes necessary for anaerobic glycolysis. Luo et al. (2011) now identify pyruvate kinase (PK)-M2 as an intriguing new interacting partner for HIF1, revealing a potential mechanism for the Warburg effect, an elevation in aerobic glycolytic metabolism frequently observed in cancer.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Terrain
سال: 2017
ISSN: 0760-5668,1777-5450
DOI: 10.4000/terrain.16426